Irene Cano, Isabel de la Torre, Jaime Muñoz-Triviño, Miguel G. Acedos, Jorge Barriuso, José L. García
Our partners at the Spanish National Research Council (CSIC) have recently published an exciting study exploring how acetate, a byproduct of CO2 capture and biomass pretreatment, can be used as a sustainable carbon source to produce 2,3-butanediol (2,3-BDO). With this research, they are finding ways to move away from food-based sugars and toward alternative feedstocks derived from industrial .
The key shift here is changing how we look at industrial side-streams. Instead of just treating them as waste to be removed, the focus is on recovering and transforming them into high-value platform chemicals. While 2,3-BDO is incredibly versatile for industrial use, the possibility of producing it from acetate has rarely been explored until now. To tackle this, the team used an engineered Escherichia coli W strain, optimizing the process through a mix of metabolic modeling and bioreactor experiments.
Irene Cano, Isabel de la Torre, Jaime Muñoz-Triviño, Miguel G. Acedos, Jorge Barriuso, José L. García. Impact of oxygen availability on Escherichia coli metabolism to produce 2,3-butanediol from acetate. Chemical Engineering Journal, Volume 524, 2025, https://doi.org/10.1016/j.cej.2025.169016.
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