Markus Schmidt, Günter Seyfried, Uliana Reutina, Zeki Seskir, Eduardo R. Miranda
Our partner Biofaction, alongside Zeki Seskir and Eduardo R. Miranda, recently published a study in Frontiers in Soft Matter exploring whether slime mold (Physarum polycephalum) could serve as a biological component to simulate quantum entanglement.
The project was built on the premise that if slime mold behaves like a memristor (a resistor that “remembers” its past electrical charge), it could potentially be used to represent the complex states of quantum bits. To investigate this, the team looked for “pinched” hysteresis curves—the specific electrical signature that identifies a memristive device.
Ultimately, the researchers found that slime mold does not actually function as a biological memristor. Despite previous claims in the literature, their experiments showed that the mold’s natural capacitance prevents it from behaving like one, meaning it cannot be used to simulate quantum entanglement.
Instead, the study discovered that slime mold is better described as a biological replacement circuit consisting of resistors and capacitors. While this rules out quantum applications, Biofaction and the research team believe the organism still holds significant potential in bio-electronics for applications such as signal filters and timing circuits.
Read the full paper here.
Schmidt M, Seyfried G, Reutina U, Seskir Z and Miranda ER (2025) From simulation to reality: experimental analysis of a quantum entanglement simulation with slime molds (Physarum polycephalum) as bioelectronic components. Front. Soft Matter 5:1588404. doi: 10.3389/frsfm.2025.1588404
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